The Korea Research Institute of Standards and Science (KRISS) announced on Oct. 13 that a research team headed by Choi Joon-hyuk from the Center for Bioanalysis at KRISS successfully developed a technology that can analyze both the recovery process of damaged DNA caused by carcinogens and various responses of cells when they are restored.
This study was jointly conducted with a U.S. research team led by Prof. Aziz Sancar from North Carolina University, who won the Nobel Prize in chemistry this year.
The method enables researchers to simultaneously monitor the recovery process of DNA after being damaged by carcinogens and numerous cell responses.
When the DNA in a cell is damaged, it is restored by many enzyme systems. DNA pieces are created during the process, and different kinds of cell responses occur, including apoptosis.
Through continuous study, the joint research team succeeded in developing a tech that can monitor a variety of cell responses at the same time.
The newly-developed technology is expected to contribute to developing a new method for medical tests, which can effectively analyze the possibility of disease occurrences resulting from carcinogens or the effectiveness of anti-cancer drugs.